Pathophysiological and therapeutic update of colonic diverticula
Keywords:
Colonoscopy, Colon diverticulitis, Diverticulum, Crohn's disease, Risk factor's, PathophysiologyAbstract
Introduction: diverticula, also described as bags or sacculations, correspond to the most frequent anatomical alteration that compromises the large intestine, specifically in the descending and sigmoid colon. It is among the main causes of digestive complications presented in emergency services, especially in elderly patients.
Objective: to characterize colonic diverticula pathophysiologically.
Methodological Design: 80 articles were identified, of which 44 were included, being more than 75% from the last 3 years; from academic search engines such as PubMed, MedLine, Ovid, ResearchGate and Google Scholar.
Development: diverticular disease of the colon affects patients of both sexes, with a mean age of over 60 years. Pathophysiologically it is characterized as a herniation of the mucosa and submucosa. Various authors have classified it according to different clinical aspects. Radiological and endoscopic studies are the primary sources for its diagnosis. As main risk factors are; smoking, obesity, sedentary lifestyle and diet with high content of animal fat. Antibiotic therapy and surgery are among the main methods for its treatment.
Conclusions: diverticular disease has a high incidence in the general population, representing a health problem in elderly patients who have multiple risk factors for developing complications. Its diagnosis is based fundamentally on radiological and endoscopic studies. Treatment based on clinical improvement is completed with outpatient antibiotic therapy.
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References
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