Pathophysiological and therapeutic update of colonic diverticula

Authors

  • Yonathan Estrada-Rodríguez Universidad de Ciencias Médicas de Matanzas. Facultad de Ciencias Médicas de Matanzas: Dr. Juan Guiteras Gener. Matanzas, Cuba.
  • Mileidys Jiménez-Ortiz Universidad de Ciencias Médicas de Matanzas. Facultad de Ciencias Médicas de Matanzas: Dr. Juan Guiteras Gener. Hospital Provincial Docente Clínico- Quirúrgico Cmdte Faustino Pérez Hernández. Matanzas, Cuba. https://orcid.org/0009-0008-5685-9208
  • Yuniel Rosales-Alcántara Universidad de Ciencias Médicas de Matanzas. Facultad de Ciencias Médicas de Matanzas: Dr. Juan Guiteras Gener. Hospital Territorial General Pedro Betancourt. Matanzas, Cuba. https://orcid.org/0000-0001-8499-9285

Keywords:

Colonoscopy, Colon diverticulitis, Diverticulum, Crohn's disease, Risk factor's, Pathophysiology

Abstract

Introduction: diverticula, also described as bags or sacculations, correspond to the most frequent anatomical alteration that compromises the large intestine, specifically in the descending and sigmoid colon. It is among the main causes of digestive complications presented in emergency services, especially in elderly patients.

Objective: to characterize colonic diverticula pathophysiologically.

Methodological Design: 80 articles were identified, of which 44 were included, being more than 75% from the last 3 years; from academic search engines such as PubMed, MedLine, Ovid, ResearchGate and Google Scholar.

Development: diverticular disease of the colon affects patients of both sexes, with a mean age of over 60 years. Pathophysiologically it is characterized as a herniation of the mucosa and submucosa. Various authors have classified it according to different clinical aspects. Radiological and endoscopic studies are the primary sources for its diagnosis. As main risk factors are; smoking, obesity, sedentary lifestyle and diet with high content of animal fat. Antibiotic therapy and surgery are among the main methods for its treatment.

Conclusions: diverticular disease has a high incidence in the general population, representing a health problem in elderly patients who have multiple risk factors for developing complications. Its diagnosis is based fundamentally on radiological and endoscopic studies. Treatment based on clinical improvement is completed with outpatient antibiotic therapy.

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Author Biographies

Yonathan Estrada-Rodríguez, Universidad de Ciencias Médicas de Matanzas. Facultad de Ciencias Médicas de Matanzas: Dr. Juan Guiteras Gener. Matanzas, Cuba.

Alumno Ayudante de Coloproctología

Mileidys Jiménez-Ortiz, Universidad de Ciencias Médicas de Matanzas. Facultad de Ciencias Médicas de Matanzas: Dr. Juan Guiteras Gener. Hospital Provincial Docente Clínico- Quirúrgico Cmdte Faustino Pérez Hernández. Matanzas, Cuba.

Servicio de Coloproctología Especialista de 1er Grado en Medicina General Integral Especialista de 1er Grado en Coloproctología

Yuniel Rosales-Alcántara, Universidad de Ciencias Médicas de Matanzas. Facultad de Ciencias Médicas de Matanzas: Dr. Juan Guiteras Gener. Hospital Territorial General Pedro Betancourt. Matanzas, Cuba.

Servicio de Coloproctología Especialista de 1er Grado en Medicina General Integral Especialista de 1er Grado en Coloproctología

References

Walter Eliseia, Antonio Tursib. (2016). Recent advances in the treatment of colonic diverticular disease and prevention of acute diverticulitis. Annals of Gastroenterology, 29, 24-32.

Yáñez E, Maturana J, Briones L. Enfermedad diverticular: nuevas perspectivas en el tratamiento dieto-terapéutico. Revista chilena de nutrición [Internet]. 2019 [citado 11 marzo 2022];(46). Disponible en: https://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-75182019000500585&lang=es

Wasvary H, Turfah F, Kadro O, Beauregard W. Same hospitalization resection for acute diverticulitis. Am Surg. 1999;65(07):632–635, discussion 636

Kaiser A M, Jiang J K, Lake J P, Ault G, Artinyan A, Gonzalez-Ruiz C, et al. The management of complicated diverticulitis and the role of computed tomography. AmJGastroenterol.2005;100(04):910–917

Published

2023-05-01

How to Cite

1.
Estrada-Rodríguez Y, Jiménez-Ortiz M, Rosales-Alcántara Y. Pathophysiological and therapeutic update of colonic diverticula. MedEst [Internet]. 2023 May 1 [cited 2024 Nov. 21];3(1):e145. Available from: https://revmedest.sld.cu/index.php/medest/article/view/145

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