ABO and Rh conflict, transfusion reactions

Authors

Keywords:

Blood, Blood groups, Hemolysis, Transfusion reactions

Abstract

Introduction: in 1667, Jean-Baptiste Denys performed the first blood transfusion between people, marking the beginning of the common practice of blood transfusion in modern medicine. Transfusion reactions can be side effects of this practice, classified as immediate or acute and delayed.

Objective: describe immediate and delayed transfusion reactions in terms of definition, diagnosis and management.

Methodological design: a search was carried out in articles published five years ago. Twenty-three articles were selected, most of them from MEDLINE, SciElo, Infomed, the Virtual Health Library of Cuba and websites such as Mayoclinic.

Development: blood transfusion can lead to transfusion reactions, including hemolytic ones, where red blood cells are destroyed. These reactions can be serious and life-threatening. Hemolysis can occur intravascularly or extravascularly. Acute reactions are caused by incompatibility of the ABO system and can be severe. Intravascular hemolysis is characterized by rapid red blood cell destruction, while extravascular hemolysis reduces red blood cell survival. Hemolytic reactions can trigger inflammatory and systemic responses in the body. Proper diagnosis and treatment are essential to prevent complications and improve clinical outcomes.

Conclusions: knowing and understanding transfusion reactions is essential to guarantee safe and effective blood transfusions. These complications can have serious and even life-threatening consequences if not properly diagnosed and treated.

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References

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Published

2024-02-11

How to Cite

1.
Chávez-Moya MO, León-de Armas L, Cruz-Coello ML. ABO and Rh conflict, transfusion reactions. MedEst [Internet]. 2024 Feb. 11 [cited 2024 Nov. 7];3(3):e201. Available from: https://revmedest.sld.cu/index.php/medest/article/view/201

Issue

Vol. 3 No. 3 (2023): SEPTIEMBRE-DICIEMBRE

Section

REVIEW ARTICLES

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