Thyroid cancer in children: a rare entity
Keywords:
Endocrinology, Thyroid Neoplasms, Child, PediatricsAbstract
Introduction: thyroid cancer in children is considered a rare disease due to its low incidence, representing less than 1% of pediatric tumors. However, it is the most prevalent childhood endocrinological tumor and its frequency has experienced a significant increase in recent years.
Objective: to highlight the differences that thyroid tumors present in children compared to adults.
Methods: 30 articles were identified, of which 23 were included, more than 75 % from the last 3 years; coming from academic search engines such as PubMed, MedLine, Ovid, ResearchGate and Google Scholar.
Development: thyroid cancer in children is diagnosed in advanced stages, when lymph node involvement and lung metastases are more frequent than in adults. However, the prognosis is excellent, except in the most aggressive tumors, which present precisely.
Conclusions: thyroid cancer in pediatrics presents peculiarities that make it different from that which occurs in adults. It has a greater influence of genetics, a greater probability of locoregional extension and metastasis at diagnosis, but on the contrary the prognosis is usually good.
Downloads
References
2.Prieto Matos P, Martín Hernández D, Martín Alonso M, Bajo Delgado AF, Riesco Riesco S, Prieto Matos C. Cáncer de tiroides en pediatría. Rev ORL. [Internet] 2021 [citado 07/02/2024]; 12(4):303-12. Disponible en: https://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S2444-79862021000400003
3.Paulson VA, Rudzinski ER, Hawkins DS. Thyroid cancer in the pediatric population. Genes (Basel) [Internet] 2019 [citado 07/02/2024]; 10(9):723. Disponible en: https://pubmed.ncbi.nlm.nih.gov/31540418/
4.Sisinni L, Gich I, Torrent M, Badell I. Neoplasias malignas secundarias después de un trasplante de progenitores hematopoyéticos en edad pediátrica. An Pediatr. [Internet] 2019 [citado 07/02/2024]; 90(3):157-64. Disponible en: https://www.sciencedirect.com/science/article/pii/S1695403318303187
5.Bible KC, Kebebew E, Brierley J, Brito JP, Cabanillas ME, Clark TJ. American Thyroid Association Guidelines for Management of Patients with Anaplastic Thyroid Cancer: American Thyroid Association Anaplastic Thyroid Cancer Guidelines Task Force. Thyroid. [Internet] 2021 [citado 07/02/2024]; 31(3):337-86. Disponible en: https://pubmed.ncbi.nlm.nih.gov/33728999/
6.Lebbink CA, Links TP, Czarniecka A, Dias RP, Elisei R, Izatt L, et al. 2022 European Thyroid Association Guidelines for the management of pediatric thyroid nodules and differentiated thyroid carcinoma, Eur Thyroid J [Internet] 2022 [citado 07/02/2024]; 11: e220146. Disponible en: https://pubmed.ncbi.nlm.nih.gov/36228315/
7.Francis GL, Waguespack SG, Bauer AJ, Angelos P, Benvenga S, Cerutti JM. Management Guidelines for Children with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Pediatric Thyroid Cancer. Thyroid. [Internet] 2015 [citado 07/02/2024]; 25(7):716-59 Disponible en: https://pubmed.ncbi.nlm.nih.gov/25900731/
8.Lavayen Alava AP, Quizhpi Paredes DE. Tratamiento Actual del Cáncer Tiroideo en Pacientes Pediátricos. MQRInvestigar [Internet]. 2023 [citado 07/02/2024]; 7(3):2505-28. Disponible en: http://www.investigarmqr.com/ojs/index.php/mqr/article/view/577
9.Agarwal S, Bychkov A, Jung CK. Emerging biomarkers in thyroid practice and research. Cancers (Basel). [Internet] 2021 [citado 07/02/2024]; 14(1):204. Disponible en: https://pubmed.ncbi.nlm.nih.gov/35008368/
10.Bernier MO, Withrow DR, Berrington de Gonzalez A, Lam CJK, Linet MS, Kitahara CM, et al. Trends in pediatric thyroid cancer incidence in the United States, 1998-2013. Cáncer. [Internet] 2019 [citado 07/02/2024]; 125(14):2497-505. Disponible en: https://pubmed.ncbi.nlm.nih.gov/31012956/
11.Howard SR, Freeston S, Harrison B, Izatt L, Natu S, Newbold K. Paediatric differentiated thyroid carcinoma: a UK National Clinical Practice Consensus Guideline. Endocr Relat Cancer. [Internet] 2022 [citado 07/02/2024]; 29(11):G1-G33. Disponible en: https://pubmed.ncbi.nlm.nih.gov/35900783/
12.Remiker AS, Chuang J, Corathers S, Rutter MM, Rutter MJ, Myer CM, et al. Differentiated thyroid cancer in the pediatric/adolescent population: Evolution of treatment: Evolution of treatment. J Pediatr Hematol Oncol. [Internet] 2019 [citado 07/02/2024]; 41(7):532-6. Disponible en: https://pubmed.ncbi.nlm.nih.gov/31033789/
13.Iizuka Y, Katagiri T, Ogura K, Mizowaki T. Comparison between the different doses of radioactive iodine ablation prescribed in patients with intermediate-to-high-risk differentiated thyroid cancer. Ann Nucl Med. [Internet] 2019 [citado 07/02/2024]; 33(7):495-501. Disponible en: https://pubmed.ncbi.nlm.nih.gov/30955202/
14.Orellana MJ, Fulle A, Carrillo D, Escobar L, Ebensperger A, Martínez R, et al. Carcinoma papilar de tiroides en un niño con hipotiroidismo congénito dishormonogénico. Reporte de un caso. Rev Chil Pediatr. [Internet] 2016 [citado 07/02/2024]; 87(6):504-9. Disponible en: https://pubmed.ncbi.nlm.nih.gov/27025990/
15.Bauer A. Cáncer de tiroides pediátrico genetica, terapéutica y resultados. Pubmed. [Internet] 2020 [citado 07/02/2024]; 49(4):589-611. Disponible en: https://pubmed.ncbi.nlm.nih.gov/33153669/
Downloads
Published
How to Cite
Issue
Section
License
Those authors who have publications with this journal accept the following terms: The authors will retain their copyright and guarantee the journal the right of first publication of their work, which will be simultaneously subject to the Recognition License. Creative Commons that allows third parties to share the work as long as its author and its first publication in this magazine are indicated. Authors may adopt other non-exclusive license agreements for the distribution of the published version of the work (e.g.: deposit it in an institutional telematic archive or publish it in a monographic volume) as long as the initial publication in this journal is indicated. Authors are allowed and recommended to disseminate their work through the Internet (e.g.: in institutional telematic archives or on your website) before and during the submission process, which can produce interesting exchanges and increase citations of the published work.
