Acute viral hepatitis type A with biphasic cholestatic behavior: Case presentation
Keywords:
Biphasic Hepatitis A, Cholestatic Hepatitis, Fulminant Hepatitis, Acute Viral HepatitisAbstract
Introduction: hepatitis A is an infectious-contagious disease of universal distribution. Where the presence of outbreaks in areas of overcrowding and poor sanitation is visualized. Although in general this disease has a favorable evolution, there are reports of complications and atypical forms of presentation such as the present case in question, which have an impact on the morbidity and mortality of patients.
Objective: to present a patient with biphasic, cholestatic behavior with Hepatitis A.
Case presentation: a 20-year-old white male patient, smoker, with the epidemiological history of having been diagnosed with hepatitis A 30 days earlier, during an outbreak in his living area, with a favorable evolution; but after the month of convalescence; It begins with marked ichterus, intense pruritus, choluria, acolia, abdominal pain in the right hypochondrium, and epixtasis. Physical examination revealed the presence of rubin ichterus, scratching lesions, and tenderness in the upper abdomen, with painful hepatomegaly of 3 cm. Therefore, he was admitted with a diagnosis of cholestatic biphasic hepatitis, the diagnosis was corroborated with the performance of pertinent complementary tests, he was treated with ursodeoxycholic acid where he had a favorable clinical evolution.
Conclusions: this study allowed us to observe the small number of cases reported with atypical presentation of Hepatitis A disease and the importance of a timely diagnosis from primary health care to prevent fatal complications of hepatitis.
Downloads
References
1. Rojas Peláez Y, Trujillo Pérez YL, Reyes Escobar AD, Bembibre Mozo D. Some considerations on the chronic viral hepatitis as a health problem. MEDISAN [Internet]. 2021 [citado 22/01/2025]; 25(4): 965-981. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1029-30192021000400965&lng=es
2. Mehta P, Reddivari AKR. Hepatitis. Treasure Island (FL): StatPearls Publishing; [Internet]. 2023 [citado 22/01/2025]. Disponible en: https://www.ncbi.nlm.nih.gov/books/NBK554549/
3. Herrera JA, Badilla J. Hepatitis A. Med. leg. Costa Rica [Internet]. 2019 [citado 22/01/2025]; 36(2):101-7. Disponible en: http://www.scielo.sa.cr/scielo.php?script=sci_arttext&pid=S1409-00152019000200101&lng=en&tlng=es
4. Jeong S, Lee H-S. Hepatitis A: Clinical manifestations and management. Intervirology [Internet]. 2010 [citado 22/01/2025]; 53(1):15-9. Disponible en: http://dx.doi.org/10.1159/000252779
5. Muñoz SG, Díaz HA, Suárez D, Sánchez JF, Gamboa A, García I, et al. Manifestaciones atípicas de la infección por el virus de la hepatitis A. Revista de Gastroenterología de México. 2018 [citado 22/01/2025]; 83(2):134-43. Disponible en: http://www.revistagastroenterologiamexico.org/es-manifestaciones-atipicas-infeccion-por-el-articulo-S0375090618300636
6. Báez Sarria F, Martinez Romero M, Ferrer Santos V, Peña Alvarez D. Hepatitis viral aguda tipo A colestásica con manifestaciones extrahepáticas y complicaciones neurológicas poco frecuentes. Rev Cubana Med Milit [Internet]. 2024 [citado 22/01/2025];53(2). Disponible en: https://revmedmilitar.sld.cu/index.php/mil/article/view/21781/2506
7. Herrera Corrales JA, Badilla García J. Hepatitis A. Med. leg. Costa Rica [Internet]. 2019 [citado 22/01/2025]; 36(2): 101-107. Disponible en: http://www.scielo.sa.cr/scielo.php?script=sci_arttext&pid=S1409-00152019000200101&lng=en
8. Castellanos-FernándezI M, Teixeira-Brado E, La-Rosa-Hernández D, Dorta-Guridi Z, Rodriguez-Pelier C, Vega-Sánchez H. Infección crónica por virus de hepatitis B. Instituto de Gastroenterología de Cuba, 2016-2018. Revista Habanera de Ciencias Médicas [Internet]. 2019 [citado 22/01/2025]; 19 (1):[aprox. 14 p.]. Disponible en: https://revhabanera.sld.cu/index.php/rhab/article/view/2669
9. Akpor Oluwaseyi A, Adelusi Folusho A, Akpor Oghenerobor B. Conocimiento, nivel de riesgo y prevalencia de la hepatitis B y C entre los conductores de minibuses comerciales en Ado-Ekiti, estado de Ekiti, Nigeria. Enferm. glob. [Internet]. 2023 [citado 22/01/2025]; 22(71): 371-406. Disponible en: http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1695-61412023000300012&lng=es
10. Velasco Martínez FI, Sandoval Suárez LJ, Ehrhardt Morón EM, Mora Bautista VM. Hepatitis colestásica persistente por virus de hepatitis A en pediatría. Reporte de Caso. Pediatria. [Internet]. 2023 [citado 22/01/2025]; 55(Suplemento 1):7-10. Disponible en: https://revistapediatria.org/rp/article/view/189
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Yasmany Salazar-Rodríguez, Aliuska Cadet-Cobas, Ibis Umpierrez-García, Thais de la Caridad Roca-Alvarez

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Those authors who have publications with this journal accept the following terms: The authors will retain their copyright and guarantee the journal the right of first publication of their work, which will be simultaneously subject to the Recognition License. Creative Commons that allows third parties to share the work as long as its author and its first publication in this magazine are indicated. Authors may adopt other non-exclusive license agreements for the distribution of the published version of the work (e.g.: deposit it in an institutional telematic archive or publish it in a monographic volume) as long as the initial publication in this journal is indicated. Authors are allowed and recommended to disseminate their work through the Internet (e.g.: in institutional telematic archives or on your website) before and during the submission process, which can produce interesting exchanges and increase citations of the published work.