Alcohol use disorder and depression as dual pathology. Case report

Autores/as

Palabras clave:

Major depressive episode ; Case report ; Suicide attempt; Alcohol use disorder

Resumen

Introduction: The comorbidity of alcohol use disorder and depression—dual pathology—carries a high suicidal risk and poor prognosis. This case is unique due to its early onset after traumatic grief and the simultaneous presentation of severe dependence, major depression, and a suicide attempt. It contributes a dual therapeutic strategy combining detoxification, pharmacotherapy, and grief-focused psychotherapy, rarely described in our setting.

Objective: To describe the diagnostic-therapeutic approach to a case of dual pathology (severe alcohol use disorder and major depressive episode) with suicidal risk.

Case Presentation: A 27-year-old male patient with daily consumption of 750 mL of rum, anhedonia, guilt, insomnia, and active suicidal ideation, plus a suicide attempt 15 days earlier with alcohol and diazepam. The main patient concerns were inability to control drinking and a feeling of emptiness. Relevant findings included AUDIT 28/40, Hamilton scale indicating severe depression, and Beck Suicidal Ideation scale showing high risk. Main diagnoses were severe alcohol use disorder, severe major depressive episode without psychotic symptoms, and complicated grief. Interventions comprised involuntary hospitalization, sertraline 50 mg/day, naltrexone 50 mg/day, and cognitive-behavioral therapy. At three months the patient remained abstinent, with significant reduction of depressive symptoms and return to work.

Conclusions: Dual pathology with suicidal risk requires concurrent and long-term management. An intervention centered on processing traumatic grief, with family and community support, offers the best chance for recovery and relapse prevention.

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Citas

1. Barroso Fontanals ME, Pacios Dorado JL, Sánchez Blanco LA. Crisis de salud mental: un problema médico vigente. Rev. estud. HolCien. [Internet]. 2024 [cited 21/01/2026];5(2). Available in:https://revholcien.sld.cu/index.php/holcien/article/view/382

2. Organización Panamericana de la Salud - PAHO. Depresión. OPS/OMS. [Internet]. 2025 [cited 21/01/2026]. Available in:https://www.paho.org/es/temas/depresion

3. Organización Mundial de la Salud. Trastorno depresivo. OMS. [Internet] 2025 [cited 21/01/2026]. Available in:https://www.who.int/es/news-room/fact-sheets/detail/depression

4. National Institute on Alcohol, Abuse and Alcoholism. Comprensión del trastorno por consumo de alcohol. Alcohol’s Effects on Health – NIH. [Internet] 2024 [cited 21/01/2026]. Available in:https://www.niaaa.nih.gov/publications/comprension-del-trastorno-por-consumo-de-alcohol

5. Hasin DS, O’Brien CP, Auriacombe M, Borges G, Bucholz K, Budney A, et al. DSM-5 Criteria for substance use disorders: recommendations and rationale. Am J Psychiatry. [Internet] 2024 [cited 21/01/2026]; 170(8):834-851. Available in:https://pmc.ncbi.nlm.nih.gov/articles/PMC3767415/

6. National Institute on Alcohol, Abuse and Alcoholism. Trastorno por consumo de alcohol: una comparación entre el DSM-IV y el DSM-5. Alcohol’s Effects on Health – NIH. [Internet] 2021 [cited 21/01/2026]. Available in:https://www.niaaa.nih.gov/publications/brochures-and-fact-sheets/trastorno-por-consumo-de-alcohol-una-comparacion-entre-el-dsm-iv-y-el-dsm-5

7. Babor TF, Higgins-Biddle JC, Saunders JB, Monteiro MG. AUDIT: The Alcohol Use Disorders Identification Test. Guidelines for use in primary care. 2nd ed. Geneva: World Health Organization; 2001. Available in:https://www.who.int/publications/i/item/WHO-MSD-MSB-01.6a

8. Hamilton M. A rating scale for depression. J Neurol Neurosurg Psychiatry. [Internet] 1960 [cited 21/01/2026];23:56-62. Available in:https://pubmed.ncbi.nlm.nih.gov/14399272/

9. Beck AT, Kovacs M, Weissman A. Assessment of suicidal intention: the Scale for Suicide Ideation. J Consult Clin Psychol. [Internet] 1979 [cited 21/01/2026];47(2):343-52. Available in:https://pubmed.ncbi.nlm.nih.gov/469082/

10. Alayón R. El consumo de sustancias, un factor de riesgo de la conducta suicida. Prevención del suicidio – SOM. [Internet] 2024 [cited 21/01/2026]. Available in:https://prevencionsuicidio.som360.org/es/articulo/consumo-sustancias-factor-riesgo-conducta-suicida

11. González de Armas CE, González Roger M, Guerra Guerra MM, Capote Bueno MI. Depresión y riesgo suicida en pacientes alcohólicos ingresados en el Servicio de Adicciones del Hospital Psiquiátrico de La Habana. Rev. Hosp. Psiq. Hab. [Internet]. 2025 [citado 21/01/2026];17(3):e181. Available in:https://revhph.sld.cu/index.php/hph/article/view/181

12. Zizzi A, Berri IM, Berri A, Occhipinti M, Escelsior A, Guglielmo R, et al. Psychological dimensions in alcohol use disorder: comparing active drinkers and abstinent patients. Front. Psychiatry. [Internet] 2024 [cited 21/01/2026]; 15. Available in:https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2024.1420508/full

13. Komischke-Konnerup KB, Zachariae R, Boelen PA, Marello MM, O'Connor M. Grief-focused cognitive behavioral therapies for prolonged grief symptoms: A systematic review and meta-analysis. J Consult Clin Psychol. [Internet] 2024 [cited 21/01/2026];92(4):236-248. Available in:https://pubmed.ncbi.nlm.nih.gov/38573714/

14. Bighelli I, Rodolico A, García-Mieres H, Pitschel-Walz G, Hansen WP, Schneider-Thoma J, et al. Psychosocial and psychological interventions for relapse prevention in schizophrenia: a systematic review and network meta-analysis. Lancet Psychiatry. [Internet] 2021 [cited 21/01/2026];8(11):969-980. Available in:https://pubmed.ncbi.nlm.nih.gov/34653393/

15. Bernal García P, Muñoz Algar MJ. Estudio de la conducta suicida en mujeres con TCA en una unidad de deshabituación alcohólica. Congreso Virtual Internacional de Psiquiatría, Psicología y Salud Mental (Interpsiquis) – XVI Edición. [Internet] 2015 [cited 21/01/2026]. Available in:https://psiquiatria.com/bibliopsiquis/estudio-de-la-conducta-suicida-en-mujeres-con-tca-en-una-unidad-de-deshabituacion-alcoholica

Publicado

08-05-2026

Cómo citar

1.
Barroso-Fontanals ME, Serra-Bauzá N de J, Herrero-Díaz A, Ramos-Labrada E. Alcohol use disorder and depression as dual pathology. Case report. MedEst [Internet]. 8 de mayo de 2026 [citado 22 de mayo de 2026];6:e520. Disponible en: https://revmedest.sld.cu/index.php/medest/article/view/520

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